Publications

    • Aharon-Hefetz N, Frumkin I, Mayshar Y, Dahan Orna#, Pilpel Yitzhak # and Rak R (2020) “Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest”. Elife. 9:e58461 (Pubmed, PDF) (# co-corresponding author)
    • Slomka S, Françoise I, Hornung H, Asraf O, Biniashvili T, Pilpel Y and Dahan Orna (2020) “Experimental Evolution of Bacillus subtilis Reveals the Evolutionary Dynamics of Horizontal Gene Transfer and Suggests Adaptive and Neutral Effects” (Pubmed, PDF)
    • Mordret Ernest #, Dahan Orna #, Asraf O, Rak R, Yehonadav A, Barnabas GD, Cox J, Geiger T, Lindner AB and Pilpel Y (2019) “Systematic Detection of Amino Acid Substitutions in Proteomes Reveals Mechanistic Basis of Ribosome Errors and Selection for Translation Fidelity” Mol Cell. 75(3):427-441 (Pubmed, PDF) (# Equal contribution)
    • Dahan Orna , Dorfman B, Sayin S, Rosener B, Hua T, Yarden A and Mitchell A (2019) “Harnessing robotic automation and web-based technologies to modernize scientific outreach”. PLoS Biol. 17(6):e3000348 (Pubmed, PDF)
    • Kaminski Strauss S, Schirman D, Jona G, Brooks AN, Kunjapur AM, Nguyen Ba AN, Flint A, Solt A, Mershin A, Dixit A, Yona AH, Csörgő B, Busby BP, Hennig BP, Pál C, Schraivogel D, Schultz D, Wernick DG, Agashe D, Levi D, Zabezhinsky D, Russ D, Sass E, Tamar E, Herz E, Levy ED, Church GM, Yelin I, Nachman I, Gerst JE, Georgeson JM, Adamala KP, Steinmetz LM, Rübsam M, Ralser, Klutstein M, Desai MM, Walunjkar N, Yin N, Hefetz NA, Jakimo N, Snitser O, Adini O, Kumar P, Smith RSH, Zeidan R, Hazan R, Rak R, Kishony R, Johnson S, Nouriel S, Vonesch SC, Foster S, Dagan T, Wein T, Karydis T, Wannier TM, Stiles T, Olin-Sandoval V, Mueller WF, Bar-On YM, Dahan Orna# and Pilpel Yitzhak# (2019) “Evolthon: A community endeavor to evolve lab evolution”. PLoS Biol. 17(3):e3000182 (Pubmed, PDF) (# Equal contribution)
    • Rak Roni #, Dahan Orna# and Pilpel Y (2018) “Repertoires of tRNAs: The Couplers of Genomics and Proteomics”. Annu Rev Cell Dev Biol. 34:239-264 (Pubmed, PDF) (# Equal contribution)
    • Bar-Yaacov D, Pilpel Y and Dahan Orna (2018) “RNA editing in bacteria: occurrence, regulation and significance”. RNABiol. 15(7):863-867 (Pubmed, PDF)
    • Bar-Yaacov D, Mordret E, Towers R, Biniashvili T, Soyris C, Schwartz S, Dahan Orna# and Pilpel Yitzhak# (2017). “RNA editing in bacteria recodes multiple proteins and regulates an evolutionarily conserved toxin-antitoxin system”. Genome Res. 27(10):1696-1703 (PubMed, PDF) (# Equal contribution)
    • Sagi D, Rak R, Gingold H, Adir I, Maayan G, Dahan Orna, Broday L, Pilpel Y and Rechavi O. (2016). “Tissue- and Time-Specific Expression of Otherwise Identical tRNA Genes”. PLoS Genet. 12(8):e1006264. (PubMed, PDF)
    • Gingold H, Tehler D, Christoffersen NR, Nielsen MM, Asmar F, Kooistra SM, Christophersen NS, Christensen LL, Borre M, Sørensen KD, Andersen LD, Andersen CL, Hulleman E, Wurdinger T, Ralfkiær E, Helin K, Grønbæk K, Ørntoft T, Waszak SM, Dahan Orna, Pedersen JS, Lund AH and Pilpel Yitzhak. (2014).  “A dual program for translation regulation in cellular proliferation and differentiation”.Cell158(6):1281-1292. (PubMed, PDF)

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Cell’s comment. 2014,158(6):1238-1239

    • Bloom-Ackermann Z, Navon S, Gingold H, Towers R, Pilpel Yitzhak and  Dahan Orna. (2014). “A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool”.PLoS Genet. 10(1):e1004084. (PubMed, PDF)
    • Yona AH, Bloom-Ackermann Z, Frumkin I, Hanson-Smith V, Charpak-Amikam Y, Feng Q, Boeke JD, Dahan Orna and Pilpel Yitzhak (2013). “tRNA genes rapidly change in evolution to meet novel translational demands”. Elife.2:e01339 (PubMed, PDF)
    • Ophir Shalem, lucas Carey, Dan Zeevi, Eilon Sharon, Adina Weinberger, Orna Dahan, Yitzhak Pilpel, and Eran Segal (2013). “Measurements of the impact of 3′ end sequences on gene expression reveal wide range and sequence dependent effects”. PLOS Computational Biol. 9(3) e1002934 (PubMed, PDF)
    • Avihu Yona, Yair Manor, Rebacca Herbst, Gal Romano, Martin Kupiec, Yitzhak Pilpel and Orna Dahan (2012). “Chromosomal duplication is a transient evolutionary solution to stress”. PNAS 109(51):21010-5 (PubMed, PDF)
    • Hila Gingold, Orna Dahan and Yitzhak Pilpel (2012). “Dynamic Changes of translation efficiency deduced by analysis of environment-dependent codon usage patterns”. Nucleic Acids Res. 40(20):10053-63 (PubMed, PDF)
    • Ophir Shalem, Bella Groisman, Mordechai Choder, Orna Dahan# and Yitzhak Pilpel# (2011). “Transcriptome kinetics is governed by a genome-wide coupling of mRNA production and degradation: a role for RNA PolII”. PLoS Genet. 7(9): e1002273 (PubMed, PDF) (# Equal contribution)
    • Orna Dahan, Hila Gingold, and Yitzhak Pilpel (2011). “Regulatory mechanisms and networks couple the various phases of gene expression”. Trends Genet. 27(8):316-22 (PubMed, PDF)
    • Tamir Tuller, Asaf Carmi, Kalin Vestsigian, Sivan Navon, Yuval Dorfan, John Zaborske, Tao Pan, Orna Dahan, Itay Furman, and Yitzhak Pilpel (2010). “An evolutionarily conserved mechanism for controlling the efficiency of protein translation”. Cell 141(2):344-54 (PubMed, PDF)

Also Featured in:
Cell, 2010, 141(2):227-229 Kurt Fredrick and Michael Ibba: “How the Sequence of a Gene Can Tune Its Translation”
Faculty of 1000 Biology, May 2010,Jonathan R Warner

    • Amir Mitchell, Gal.H.Romano, Martin Kupiec, Orna Dahan#, and Yitzhak Pilpel# (2009). “Adaptive prediction of environmental changes by microorganisms”. Nature 460(7252):220-4 (PubMed, PDF) (# Equal contribution)

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Nature’s news and views. 2009, 460(7252):181 “Evolutionary biology: Microbes exploit groundhog day”
Nature Microbiology Reviews. 2009,7, 550 “Microbial genetics: Predicting the future”
Cell. 2009,138(3):409 “Evolutionary Biology Select: Microbes Do More than Hedge Their Bets”
Faculty of 1000 Biology Oct 2009, Yves Van de Peer | John Marra

    • Ophir Shalem, Orna Dahan, Michal Levo1, Maria Rodriguez Martinez1, Itay Furman, Eran Segal, and Yitzhak Pilpel (2008). “Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation”. Mol Syst Biol. 4:223 (PubMed, PDF)

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Faculty of 1000 Biology Feb 2009, Jurg Bahler

    • Kafri Ran #, Dahan Orna#, and Yitzhak Pilpel (2008). “Preferential protection of protein interaction network hubs in yeast: evolved functionality of genetic redundancy”. PNAS 105(4):1243-8 (PubMed, PDF) (# Equal contribution)
    • Dahan Orna and Martin Kupiec (2004). “The Saccharomyces cerevisiae gene CDC40/PRP17 controls cell cycle progression through splicing of the ANC1 gene”. Nucleic Acids Res. 32(8):2529-40 (PubMed, PDF)
    • Dahan Orna and Martin Kupiec (2002). “Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint”. Nucleic Acids Res. 30(20):4361-70 (PubMed, PDF)